Mechanism of Polycomb recruitment to CpG islands revealed by inherited disease-associated mutation

Mechanism of Polycomb recruitment to CpG islands revealed by inherited disease-associated mutation

How the transcription repressing complex Polycomb interacts with transcriptional regulators at housekeeping genes in somatic cells is not well understood. By exploiting a CpG island (CGI) point mutation causing a Mendelian disease, we show that DNA binding of activating transcription factor (TF) det...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Caputo, VS, Costa, JR, Makarona, K, Georgiou, E, Layton, DM, Roberts, I, Karadimitris, A
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Oxford University Press 2013

Những quyển sách tương tự

CpG island structure and trithorax/polycomb chromatin domains in human cells
Bằng: Orlando, David A., et al.
Được phát hành: (2016)

Polycomb-like proteins link the PRC2 complex to CpG islands
Bằng: Li, H, et al.
Được phát hành: (2017)

An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment
Bằng: Lynch, MD, et al.
Được phát hành: (2012)

KDM2B links recognition of CpG islands to polycomb domain formation in vivo
Bằng: Farcas, AM
Được phát hành: (2013)

An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.
Bằng: Lynch, MD, et al.
Được phát hành: (2012)

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.
Bằng: Julie Hunkapiller, et al.
Được phát hành: (2012-01-01)

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
Bằng: Farcas, A, et al.
Được phát hành: (2012)

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
Bằng: Anca M Farcas, et al.
Được phát hành: (2012-12-01)

Keep Fingers on the CpG Islands
Bằng: Xing Zhang, et al.
Được phát hành: (2024-06-01)

Bidding the CpG island goodbye
Bằng: John M Greally
Được phát hành: (2013-02-01)

Prediction of CpG-island function: CpG clustering vs. sliding-window methods
Bằng: Luque-Escamilla Pedro L, et al.
Được phát hành: (2010-05-01)

Loss of CpG island immunity to DNA methylation induced by mutation
Bằng: Bernhard Horsthemke, et al.
Được phát hành: (2023-05-01)

CpG islands recruit a histone H3 lysine 36 demethylase.
Bằng: Blackledge, N, et al.
Được phát hành: (2010)

Epigenetic inheritance is unfaithful at intermediately methylated CpG sites
Bằng: Amir D. Hay, et al.
Được phát hành: (2023-09-01)

A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes
Bằng: Yueyuan Zheng, et al.
Được phát hành: (2021-04-01)

CpGPAP: CpG island predictor analysis platform
Bằng: Chuang Li-Yeh, et al.
Được phát hành: (2012-03-01)

CpG island mapping by epigenome prediction.
Bằng: Christoph Bock, et al.
Được phát hành: (2007-06-01)

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?
Bằng: Han Leng, et al.
Được phát hành: (2009-02-01)

In silico identification of single nucleotide variations at CpG sites regulating CpG island existence and size
Bằng: Nivas Shyamala, et al.
Được phát hành: (2022-03-01)

Cell-type-specific transcriptional regulation of PIGM underpins the divergent hematologic phenotype in inherited GPl deficiency.
Bằng: Costa, J, et al.
Được phát hành: (2014)

Understanding the role of CFP1 at CpG islands
Bằng: Brown, D
Được phát hành: (2014)

Evolution of CpG-islands by means of tandem duplications
Bằng: V. N. Babenko, et al.
Được phát hành: (2017-02-01)

Semiautomatic detection of DNA methylation at CpG islands
Bằng: Kyeong-Man Hong, et al.
Được phát hành: (2005-03-01)

Intragenic CpG Islands and Their Impact on Gene Regulation
Bằng: James A. Cain, et al.
Được phát hành: (2022-02-01)

CpG islands: starting blocks for replication and transcription.
Bằng: Marie-Noëlle Prioleau
Được phát hành: (2009-04-01)

CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers
Bằng: Osamu Maruyama, et al.
Được phát hành: (2022-09-01)

Publisher Correction: A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes
Bằng: Yueyuan Zheng, et al.
Được phát hành: (2021-06-01)

Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation.
Bằng: Valérie Grandjean, et al.
Được phát hành: (2007-01-01)

<it>CpGcluster</it>: a distance-based algorithm for CpG-island detection
Bằng: Carpena Pedro, et al.
Được phát hành: (2006-10-01)

Maternal obesity alters methylation level of cytosine in CpG island for epigenetic inheritance in fetal umbilical cord blood
Bằng: Zhuoyao Ma, et al.
Được phát hành: (2022-08-01)

CpG island chromatin: a platform for gene regulation.
Bằng: Blackledge, N, et al.
Được phát hành: (2011)

CpG-Islands as Markers for Liquid Biopsies of Cancer Patients
Bằng: Maximilian Sprang, et al.
Được phát hành: (2020-08-01)

Comparative analysis of CpG islands among HBV genotypes.
Bằng: Yongmei Zhang, et al.
Được phát hành: (2013-01-01)

Long-range autocorrelations of CpG islands in the human genome.
Bằng: Benjamin Koester, et al.
Được phát hành: (2012-01-01)

CpG island methylation of <it>TMS1</it>/<it>ASC </it>and <it>CASP8 </it>genes in cervical cancer
Bằng: Tamandani DM, et al.
Được phát hành: (2009-02-01)

CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands
Bằng: Louie N. van de Lagemaat, et al.
Được phát hành: (2018-10-01)

CpG-creating mutations are costly in many human viruses
Bằng: Caudill, VR, et al.
Được phát hành: (2020)

Mutation saturation for fitness effects at human CpG sites
Bằng: Ipsita Agarwal, et al.
Được phát hành: (2021-11-01)

Biochemical isolation and mass spectrometric analysis of the CpG island proteome
Bằng: Kaya, D
Được phát hành: (2022)

Mechanisms for CpG Island Methylation during X chromosome inactivation
Bằng: Yasmin, K
Được phát hành: (2024)