Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics.
Matrix metalloproteinases (MMPs) play a central role in many biological processes such as development, morphogenesis and wound healing, but their unbalanced activities are implicated in numerous disease processes such as arthritis, cancer metastasis, atherosclerosis, nephritis and fibrosis. One of t...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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