Lethal malaria: Marchiafava and Bignami were right.

One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunc...

Полное описание

Библиографические подробности
Главные авторы: White, N, Turner, G, Day, N, Dondorp, A
Формат: Journal article
Язык:English
Опубликовано: 2013
Описание
Итог:One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunctive interventions, which have either been ineffective or harmful. Recent evidence strongly suggests that Marchiafava and Bignami were right.