Predicting cross-reactivity and antigen specificity of T cell receptors

Predicting cross-reactivity and antigen specificity of T cell receptors

Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, therapeutic and pharmaceutical applications. Herein, w...

Full description

Bibliographic Details
Main Authors:	Lee, CH, Salio, M, Napolitani, G, Ogg, G, Simmons, A, Koohy, H
Format:	Journal article
Language:	English
Published:	Frontiers Media 2020

Similar Items

Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors
by: Chloe H. Lee, et al.
Published: (2020-10-01)

Potential CD8+ T cell cross-reactivity against SARS-CoV-2 conferred by other coronavirus strains
by: Lee, CH, et al.
Published: (2020)

Potential CD8+ T Cell Cross-Reactivity Against SARS-CoV-2 Conferred by Other Coronavirus Strains
by: Chloe H. Lee, et al.
Published: (2020-11-01)

A comparison of clustering models for inference of T cell receptor antigen specificity
by: Hudson, D, et al.
Published: (2023)

A comparison of clustering models for inference of T cell receptor antigen specificity
by: Dan Hudson, et al.
Published: (2024-03-01)

Higher frequencies of antigen-specific CD1a-restricted T cells in patients with atopic dermatitis
by: Jarrett, R, et al.
Published: (2014)

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses
by: Napolitani, G, et al.
Published: (2018)

Elevated and cross‐responsive CD1a‐reactive T cells in bee and wasp venom allergic individuals
by: Subramaniam, S, et al.
Published: (2015)

Quantitation of antigen-specific CD8+ T-cell responses.
by: Ogg, G, et al.
Published: (1999)

Detection of antigen-specific cytotoxic T lymphocytes: significance for investigative dermatology.
by: Ogg, G
Published: (2000)

Antigen dose and keratinocyte antigen presentation are specific determinants of T cell function in atopic eczema
by: Chan, H, et al.
Published: (2011)

Tracking Antigen-Specific T-Cells during Clinical Tolerance Induction in Humans
by: Aslam, A, et al.
Published: (2010)

Tracking antigen-specific T-cells during clinical tolerance induction in humans.
by: Aslam, A, et al.
Published: (2010)

Cross-reactivity of hepatitis C virus specific vaccine-induced T cells at immunodominant epitopes.
by: Kelly, C, et al.
Published: (2015)

T-cell receptor degeneracy promotes Th2 cytokine production at sites of low antigen concentration
by: Chan, H, et al.
Published: (2009)

Analysis of rabbit cell surface (CD) antigens by means of cross-reactive monoclonal antibodies with specificity for cattle CD antigens
by: M. Simon, et al.
Published: (2009-06-01)

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease
by: Preciado-Llanes, L, et al.
Published: (2020)

Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.
by: Salio, M, et al.
Published: (2013)

Quantitating T cell cross-reactivity for unrelated peptide antigens.
by: Ishizuka, J, et al.
Published: (2009)

T cell receptor sequence clustering and antigen specificity
by: M Vujovic, et al.
Published: (2020)

A transfer-learning approach to predict antigen immunogenicity and T-cell receptor specificity
by: Barbara Bravi, et al.
Published: (2023-09-01)

Antigen specificity and cross-reactivity drive functionally diverse anti–Aspergillus fumigatus T cell responses in cystic fibrosis
by: Carsten Schwarz, et al.
Published: (2023-03-01)

T cell receptor sequence clustering and antigen specificity
by: Milena Vujovic, et al.
Published: (2020-01-01)

Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering.
by: Viola, A, et al.
Published: (1997)

Antigen-specific B cells reactivate an effective cytotoxic T cell response against phagocytosed Salmonella through cross-presentation.
by: Jelle de Wit, et al.
Published: (2010-01-01)

Species-specific and cross-reactive antigen of filarial worm: Brugia malayi and Setaria digitata
by: Ashok Kumar Satapathy, et al.
Published: (2019-01-01)

Predicting Antigen‐Specificities of Orphan T Cell Receptors from Cancer Patients with TCRpcDist
by: Marta A. S. Perez, et al.
Published: (2024-10-01)

Statistical physics of T cell receptor development and antigen specificity
by: Košmrlj, Andrej, 1981-
Published: (2012)

Role of Specific B-Cell Receptor Antigens in Lymphomagenesis
by: Lorenz Thurner, et al.
Published: (2020-12-01)

Filaggrin-insufficiency in keratinocytes influences responsiveness of allergen-specific T cells to cognate antigen and compounds barrier function deficiency.
by: Marwah, I, et al.
Published: (2014)

Tracking antigen-specific T-cells during clinical tolerance induction in humans.
by: Aamir Aslam, et al.
Published: (2010-06-01)

Anti-lymphocyte function associated antigen-1 inhibits T-helper 2 function of human allergen-specific CD4+ T cells.
by: Ardern-Jones, MR, et al.
Published: (2008)

Efficient priming of antigen-specific cytotoxic T lymphocytes by human cord blood dendritic cells.
by: Salio, M, et al.
Published: (2003)

Antigen-specific T cell activation independently of the MHC: chimeric antigen receptor (CAR)-redirected T cells.
by: Hinrich eAbken, et al.
Published: (2013-11-01)

1297 Latent human herpesvirus 6 is reactivated in chimeric antigen receptor T cells
by: Caleb A Lareau
Published: (2023-11-01)

Kinetics and antigen specificity of CD4(+) memory and regulatory T cells during cutaneous immune responses to Varicella zoster
by: Vukmanovic-Stejic, M, et al.
Published: (2011)

Antigenic cross-reactivity of plasmodium falciparum antigens expressed in escherichia coli
by: Luiz Shozo Ozaki, et al.
Published: (1986-01-01)

MLC and CMC reactivity and specificity of idiotype-specific lymphoid cells enriched for histocompatibility (H-2) antigens.
by: Folks, T, et al.
Published: (1979)

Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
by: Todd M Brusko, et al.
Published: (2010-07-01)

Association of cellular immunity with severity of COVID-19 from the perspective of antigen-specific memory T cell responses and cross-reactivity
by: Shin-ichiro Fujii, et al.
Published: (2022-11-01)