Predicting cross-reactivity and antigen specificity of T cell receptors

Predicting cross-reactivity and antigen specificity of T cell receptors

Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, therapeutic and pharmaceutical applications. Herein, w...

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Detalles Bibliográficos
Main Authors:	Lee, CH, Salio, M, Napolitani, G, Ogg, G, Simmons, A, Koohy, H
Formato:	Journal article
Idioma:	English
Publicado:	Frontiers Media 2020

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