Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.

Here, we report the successful design, construction, and characterization of a 770-kilobase synthetic yeast chromosome II (synII). Our study incorporates characterization at multiple levels-including phenomics, transcriptomics, proteomics, chromosome segregation, and replication analysis-to provide...

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Bibliographic Details
Main Authors:	Shen, Y, Wang, Y, Chen, T, Gao, F, Gong, J, Abramczyk, D, Walker, R, Zhao, H, Chen, S, Liu, W, Luo, Y, Müller, C, Paul-Dubois-Taine, A, Alver, B, Stracquadanio, G, Mitchell, L, Luo, Z, Fan, Y, Zhou, B, Wen, B, Tan, F, Zi, J, Xie, Z, Li, B, Yang, K, Richardson, S, Jiang, H, French, C, Nieduszynski, C, Koszul, R, Marston, A, Yuan, Y, Wang, J, Bader, J, Dai, J, Boeke, J, Xu, X, Cai, Y, Yang, H
Format:	Journal article
Language:	English
Published:	American Association for the Advancement of Science 2017

Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.

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