Pyrroloimidazolediones derived from aminomalonates and benzaldehydes

Bicyclic lactams can be prepared from diethyl aminomalonate and substituted benzaldehydes by formation of a dimerised imidazolidine cycloadduct followed by a Dieckmann ring closure. The resulting N,N-heterocycles are metal-chelating but show no antibacterial activity.

Bibliographic Details
Main Authors: O’Shaughnessy, L, Hutchinson, C, Waldron, A, Christensen, KE, Moloney, MG
Format: Journal article
Language:English
Published: Thieme Publishing 2021