Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

enofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen. However, the full spectrum of reverse transcriptase (RT) mutations selected in individua...

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Main Authors: Rhee, S, Varghese, V, Holmes, S, Van Zyl, G, Steegen, K, Boyd, M, Cooper, D, Nsanzimana, S, Saravanan, S, Charpentier, C, de Oliveira, T, Etiebet, M, Garcia, F, Goedhals, D, Gomes, P, Günthard, H, Hamers, R, Hoffmann, C, Hunt, G, Jiamsakul, A, Kaleebu, P, Kanki, P, Kantor, R, Kerschberger, B, Marconi, V, D'amour Ndahimana, J, Ndembi, N, Ngo-Giang-Huong, N, Rokx, C, Santoro, M, Schapiro, J, Schmidt, D, Seu, L, Sigaloff, K, Sirivichayakul, S, Skhosana, L, Sunpath, H, Tang, M, Yang, C, Carmona, S, Gupta, R, Shafer, R
Format: Journal article
Published: Elsevier 2017