Development of mycobacterial growth inhibition assays for the early evaluation and gating of novel TB vaccine candidates

Development of mycobacterial growth inhibition assays for the early evaluation and gating of novel TB vaccine candidates

<p>Tuberculosis poses a serious global health threat, with an estimated 9 million new cases and 1.5 million deaths annually. The current vaccine, BCG, is inadequate but development of an effective alternative is severely hampered by the lack of an immune correlate of protection. Candidate vacc...

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Bibliografiske detaljer
Hovedforfatter:	Tanner, R
Andre forfattere:	McShane, H
Format:	Thesis
Sprog:	English
Udgivet:	2015
Fag:	Tuberculosis

Lignende værker

A mycobacterial growth inhibition assay (MGIA) for bovine TB vaccine development
af: Pepponi, I, et al.
Udgivet: (2017)

Tools for Assessing the Protective Efficacy of TB Vaccines in Humans: in vitro Mycobacterial Growth Inhibition Predicts Outcome of in vivo Mycobacterial Infection
af: Rachel Tanner, et al.
Udgivet: (2020-01-01)

In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection
af: Hyejon Lee, et al.
Udgivet: (2019-04-01)

Mycobacterial glycoproteins: a novel subset of vaccine candidates
af: Antonio eFacciuolo, et al.
Udgivet: (2014-09-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells
af: Tanner, R, et al.
Udgivet: (2021)

Development and application of the direct mycobacterial growth inhibition assay: a systematic review
af: Hannah Painter, et al.
Udgivet: (2024-02-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells [version 1; peer review: 2 approved]
af: Rachel Tanner, et al.
Udgivet: (2021-03-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells [version 2; peer review: 2 approved]
af: Rachel Tanner, et al.
Udgivet: (2021-09-01)

Tools for assessing the protective efficacy of TB vaccines in humans: in vitro mycobacterial growth inhibition predicts outcome of in vivo mycobacterial infection
af: Tanner, R, et al.
Udgivet: (2020)

Evaluating the effect of BCG vaccination on a whole-blood mycobacterial growth inhibition assay (BACTEC MGIT)
af: Tanner, R, et al.
Udgivet: (2011)

In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy
af: Mcshane, H, et al.
Udgivet: (2017)

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
af: Tanner, R, et al.
Udgivet: (2021)

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
af: Rachel Tanner, et al.
Udgivet: (2021-01-01)

The fall of the mycobacterial cell wall: interrogating peptidoglycan synthesis for novel anti-TB agents
af: Cheng-Yu Chiang, et al.
Udgivet: (2024-11-01)

Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth
af: Lianhua Qin, et al.
Udgivet: (2024-11-01)

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection
af: Matthew K. O'Shea, et al.
Udgivet: (2018-12-01)

Evaluation of Lionex TB kits and mycobacterial antigens for IgG and IgA detection in cerebrospinal fluid from tuberculosis meningitis patients
af: Isabela Gama Sardella, et al.
Udgivet: (2010-08-01)

The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays
af: Tanner, R, et al.
Udgivet: (2017)

Development and application of the direct mycobacterial growth inhibition assay: a systematic review
af: Painter, H, et al.
Udgivet: (2024)

RUTI Vaccination Enhances Inhibition of Mycobacterial Growth ex vivo and Induces a Shift of Monocyte Phenotype in Mice
af: Satria A. Prabowo, et al.
Udgivet: (2019-04-01)

Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains
af: Painter, H, et al.
Udgivet: (2024)

Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates
af: Nuttaporn Samart, et al.
Udgivet: (2018-11-01)

Reversing BCG-mediated autophagy inhibition and mycobacterial survival to improve vaccine efficacy
af: Maria Gonzalez-Orozco, et al.
Udgivet: (2022-09-01)

A modified mycobacterial growth inhibition assay for the functional assessment of vaccine-mediated immunity
af: Emil Joseph Vergara, et al.
Udgivet: (2024-07-01)

Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection
af: Matthew K. O’Shea, et al.
Udgivet: (2018-09-01)

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb).
af: Marsay, L, et al.
Udgivet: (2013)

Evaluation of the Performance of QuantiFERON-TB Gold Plus Assay in Human Immunodeficiency Virus Infection
af: Melike YAŞAR DUMAN, et al.
Udgivet: (2022-08-01)

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb)
af: Marsay, L, et al.
Udgivet: (2013)

Comparison of three mycobacterial DNA extraction methods from extrapulmonary samples for PCR assay
af: Khandaker Shadia, et al.
Udgivet: (2012-01-01)

Adaption of the ex vivo mycobacterial growth inhibition assay for use with murine lung cells
af: Painter, H, et al.
Udgivet: (2020)

The cross-species mycobacterial growth inhibition assay (MGIA) project 2010-2014
af: Brennan, M, et al.
Udgivet: (2017)

Adaption of the ex vivo mycobacterial growth inhibition assay for use with murine lung cells
af: Hannah Painter, et al.
Udgivet: (2020-02-01)

The TAM-TB Assay—A Promising TB Immune-Diagnostic Test With a Potential for Treatment Monitoring
af: Mohamed I. M. Ahmed, et al.
Udgivet: (2019-02-01)

Identification and selection of novel mycobacterial antigens using immunopeptidomics and immunoinformatics for the development of subunit vaccines against tuberculosis
af: Almujri, SS
Udgivet: (2022)

Characterisation of antibody responses induced by BCG and other TB vaccines to inform future vaccine design
af: Peralta Alvarez, MP
Udgivet: (2023)

From pathogenesis to antigens: the key to shaping the future of TB vaccines
af: Haoyan Yang, et al.
Udgivet: (2024-07-01)

PROTECTIVE EFFECT INDUCED BY THE NEW SUBUNIT TUBERCULOSIS VACCINE WHEN USED AS A BCG BOOST IS ASSOCIATED WITH INHIBITION OF MYCOBACTERIAL DISSEMINATION
af: V. V. Yeremeev, et al.
Udgivet: (2019-07-01)

PROTECTIVE EFFECT INDUCED BY THE NEW SUBUNIT TUBERCULOSIS VACCINE WHEN USED AS A BCG BOOST IS ASSOCIATED WITH INHIBITION OF MYCOBACTERIAL DISSEMINATION
af: Vladimir Yeremeev, et al.
Udgivet: (2019-03-01)

Shifting Mycobacterial Serine Hydrolase Activity Visualized Using Multi-Layer In-Gel Activity Assays
af: Allison L. Goss, et al.
Udgivet: (2024-07-01)

Update on TB Vaccine Pipeline
af: Carlos Martin, et al.
Udgivet: (2020-04-01)