PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders.
Variation in genes encoding costimulatory molecules expressed on lymphocytes has been expected to contribute to the genetic component of inflammatory disease, but only the gene encoding the inhibitory protein, CTLA-4, seems consistently to confer disease susceptibility. Studies in murine models impl...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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