Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab.

PURPOSE: Anti-vascular endothelial growth factor therapy enhances the activity of radiotherapy in experimental models, and bevacizumab has therapeutic activity in patients with metastatic colorectal cancer. EXPERIMENTAL DESIGN: Twenty-two patients with locally advanced inoperable colorectal carcino...

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Bibliographic Details
Main Authors: Koukourakis, M, Giatromanolaki, A, Sheldon, H, Buffa, F, Kouklakis, G, Ragoussis, I, Sivridis, E, Harris, A
Format: Journal article
Language:English
Published: 2009