The role of mitochondrial dysfunction and ER stress in TDP-43 and C9ORF72 ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the motor system with complex determinants, including genetic and non-genetic factors. Despite this heterogeneity, a key pathological signature is the mislocalization and aggregation of specific proteins in the cytoplasm, suggesti...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Frontiers Media SA
2021
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