Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of oseltamivir and its metabolite oseltamivir carboxylate in plasma, saliva and urine.

A bioanalytical method for the analysis of oseltamivir (OP) and its metabolite oseltamivir carboxylate (OC) in human plasma, saliva and urine using off-line solid-phase extraction and liquid chromatography coupled to positive tandem mass spectroscopy has been developed and validated. OP and OC were...

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Autors principals: Lindegårdh, N, Hanpithakpong, W, Wattanagoon, Y, Singhasivanon, P, White, N, Day, N
Format: Journal article
Idioma:English
Publicat: 2007