Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells.

1. The glucose and ATP dependence of exocytosis were investigated in single mouse pancreatic B-cells by monitoring changes in cell capacitance evoked by voltage-clamp depolarizations, infusion of high [Ca2+]i buffers or photorelease of caged Ca2+ or ATP. 2. In intact B-cells, using the perforated pa...

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Bibliografische gegevens
Hoofdauteurs: Eliasson, L, Renström, E, Ding, W, Proks, P, Rorsman, P
Formaat: Journal article
Taal:English
Gepubliceerd in: 1997