Delivering RNA interference to the mammalian brain.

RNA interference (RNAi) is a new modality in gene therapy which can elicit down-regulation of gene expression and has enormous potential in the treatment of neurological diseases. RNAi is a conserved system through which double stranded RNA (dsRNA) guides sequence specific mRNA degradation. The RNAi...

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Bibliographic Details
Main Authors: Fountaine, T, Wood, M, Wade-Martins, R
Format: Journal article
Language:English
Published: 2005