Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis

As a protective envelope surrounding the bacterial cell, the peptidoglycan sacculus is a site of vulnerability and an antibiotic target. Peptidoglycan components, assembled in the cytoplasm, are shuttled across the membrane in a cycle that uses undecaprenyl-phosphate. A product of peptidoglycan synt...

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Detalhes bibliográficos
Main Authors: El Ghachi, M, Howe, N, Huang, C, Olieric, V, Warshamanage, R, Touzé, T, Weichert, D, Stansfeld, P, Wang, M, Kerff, F, Caffrey, M
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2018