Humidity control as a strategy for lattice optimization applied to crystals of HLA-A*1101 complexed with variant peptides from dengue virus.

T-cell recognition of the antigenic peptides presented by MHC class I molecules normally triggers protective immune responses, but can result in immune enhancement of disease. Cross-reactive T-cell responses may underlie immunopathology in dengue haemorrhagic fever. To analyze these effects at the m...

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Main Authors: Chotiyarnwong, P, Stewart-Jones, G, Tarry, M, Dejnirattisai, W, Siebold, C, Koch, M, Stuart, D, Harlos, K, Malasit, P, Screaton, G, Mongkolsapaya, J, Jones, E
格式: Journal article
语言:English
出版: 2007