The role of Sp1 and NF-kappa B in regulating CD40 gene expression.

The role of Sp1 and NF-kappa B in regulating CD40 gene expression.

CD40 is a member of the tumor necrosis factor receptor superfamily and is a key signaling molecule expressed by antigen-presenting cells of the immune system. In a previous paper, we demonstrated that the expression of CD40 is regulated by both post-transcriptional and post-translational processes....

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Tone, M, Tone, Y, Babik, J, Lin, C, Waldmann, H
Materialtyp:	Journal article
Språk:	English
Publicerad:	2002

Liknande verk

Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer.
av: Tone, Y, et al.
Publicerad: (2014)

IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3.
av: Tone, M, et al.
Publicerad: (2000)

Regulation of CD40 function by its isoforms generated through alternative splicing.
av: Tone, M, et al.
Publicerad: (2001)

Expression of murine IL-12 is regulated by translational control of the p35 subunit.
av: Babik, J, et al.
Publicerad: (1999)

Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes.
av: Tone, Y, et al.
Publicerad: (1996)

Regulation of IL-18 (IFN-gamma-inducing factor) gene expression.
av: Tone, M, et al.
Publicerad: (1997)

Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region.
av: Powell, M, et al.
Publicerad: (2000)

NF-kappaB regulates androgen receptor expression and prostate cancer growth.
av: Zhang, L, et al.
Publicerad: (2009)

Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
av: Andreakos, E, et al.
Publicerad: (2006)

TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2.
av: Ogawa, C, et al.
Publicerad: (2014)

Structure and chromosomal location of mouse and human CD52 genes.
av: Tone, M, et al.
Publicerad: (1999)

NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
av: Smith, C, et al.
Publicerad: (2001)

Haploid reporter screens aimed at identification of NF-kappaB regulators
av: Lee, Clarissa Ci
Publicerad: (2014)

The lack of NF-kappa B transactivation and PKC epsilon expression in CD4(+)CD8(+) thymocytes correlates with negative selection.
av: Simon, A, et al.
Publicerad: (2000)

Gene structure of human CD59 and demonstration that discrete mRNAs are generated by alternative polyadenylation.
av: Tone, M, et al.
Publicerad: (1992)

Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.
av: Tait, S, et al.
Publicerad: (2000)

Sharp injury to articular cartilage activates JNK and NF kappa B and induces expression of inflammatory response genes
av: Watt, F, et al.
Publicerad: (2006)

VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
av: Kiriakidis, S, et al.
Publicerad: (2003)

VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
av: Kiriakidis, S, et al.
Publicerad: (2003)

Activation of nuclear factor-kappa B (NF-kappa B)in diarrhoea predominant irritable bowel syndrome
av: O'Sullivan, M, et al.
Publicerad: (2001)

Visualization of lymphatic vessels through NF-kappaB activity.
av: Saban, MR, et al.
Publicerad: (2004)

Quantitative prediction of NF-kappa B DNA-protein interactions.
av: Udalova, I, et al.
Publicerad: (2002)

Delayed maturation of cortical infarction: Role of caspases and NF-kappa B-mediated transcription
av: Buchan, A
Publicerad: (2001)

Investigating the role of intra- and extra-cellular modulators of the transcription factor NF-kappaB
av: Nguyen, Hung Nhat
Publicerad: (2012)

Interleukin-4 inhibits kappa light chain expression and NF kappa B activation but not I kappa B alpha degradation in 70Z/3 murine pre-B cells.
av: Clarke, C, et al.
Publicerad: (1995)

NF-kappa B regulates mica expression in arterial endothelial cell through a genetically inhibitable transcriptional control site - implications for atherosclerosis
av: Lin, D, et al.
Publicerad: (2011)

A role for the receptor tyrosine kinase Axl in regulating NF-kappa B activity in cutaneous squamous cell carcinomas
av: Papadakis, E, et al.
Publicerad: (2009)

The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.
av: Sperone, A, et al.
Publicerad: (2011)

The CD59 antigen--a multifunctional molecule.
av: Walsh, L, et al.
Publicerad: (1992)

Fibroblastic stromal cells express receptor activator of NF-kappa B ligand and support osteoclast differentiation.
av: Quinn, J, et al.
Publicerad: (2000)

Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?
av: Feldmann, M, et al.
Publicerad: (2002)

NF-[kappa]B/Rel transcription factor family / [electronic resource]
av: Liou, Hsiou-Chi, et al.
Publicerad: (2006)

Functional characterization of the NF-kappa B transcription factor gene REL2 from Anopheles gambiae
av: Hoa, N, et al.
Publicerad: (2007)

Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.
av: Walsh, L, et al.
Publicerad: (1991)

Real-time in vivo analysis of NF-kappaB activation reveals a role for the liver as a regulator of acute brain inflammation
av: Mann, D, et al.
Publicerad: (2006)

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.
av: Gyrd-Hansen, M, et al.
Publicerad: (2010)

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.
av: Brummelkamp, T, et al.
Publicerad: (2003)

In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology.
av: Suvas, S, et al.
Publicerad: (2005)

Severity of asthma: the role of CD25+,CD30+, NF-κB, and apoptotic markers
av: Abdulamir, Ahmed Sahib, et al.
Publicerad: (2009)

High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.
av: Tone, M, et al.
Publicerad: (1999)