Molecular diagnosis of the 5q deletion in malignant myeloid disorders.

The 5q-chromosome is found in a spectrum of malignant myeloid disorders (1). The 5q deletion is the most commonly reported deletion in the myelodysplastic syndromes (MDS) and is found in 10-l5% of patients (1). The 5q-chromosome occurs as a sole karyotypic abnormality in the distinct myelodysplastic...