Rebuilding a superenhancer to investigate the additive and synergistic effects of its individual components
Superenhancers are clusters of putative enhancers, densely occupied by histone 3 lysine 27 acetylation, transcription factors, and coactivators such as the mediator complex. There is a tendency for superenhancers to regulate key cell-type-specific genes, and their dysregulation is often associated w...
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| Format: | Thesis |
| Language: | English |
| Published: |
2023
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