Sonic Hedgehog regulates thymic epithelial cell differentiation

Sonic Hedgehog (Shh) is expressed in the thymus, where it regulates T cell development. Here we investigated the influence of Shh on thymic epithelial cell (TEC) development. Components of the Hedgehog (Hh) signalling pathway were expressed by TEC, and use of a Gli Binding Site-green fluorescence pr...

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Bibliographic Details
Main Authors: Saldana, J, Solanki, A, Lau, C, Sahni, H, Ross, S, Furmanski, A, Ono, M, Hollander, G, Crompton, T
Format: Journal article
Published: Elsevier 2016