The common p.R114W HNF4A mutation causes a distinct clinical subtype of monogenic diabetes

HNF4A mutations cause increased birth weight, transient neonatal hypoglycemia, and maturity onset diabetes of the young (MODY). The most frequently reported HNF4A mutation is p.R114W (previously p.R127W), but functional studies have shown inconsistent results; there is a lack of cosegregation in som...

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Bibliografske podrobnosti
Main Authors: Laver, T, Colclough, K, Shepherd, M, Patel, K, Houghton, J, Dusatkova, P, Pruhova, S, Morris, A, Palmer, C, McCarthy, M, Ellard, S, Hattersley, A, Weedon, M
Format: Journal article
Jezik:English
Izdano: American Diabetes Association 2016