Structural features of the reprolysin atrolysin C and tissue inhibitors of metalloproteinases (TIMPs) interaction.

Atrolysin C is a P-I snake venom metalloproteinase (SVMP) from Crotalus atrox venom, which efficiently degrades capillary basement membranes, extracellular matrix, and cell surface proteins to produce hemorrhage. The tissue inhibitors of metalloproteinases (TIMPs) are effective inhibitors of matrix...

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Bibliographic Details
Main Authors: Pinto, A, Terra, R, Guimarães, J, Kashiwagi, M, Nagase, H, Serrano, S, Fox, J
Format: Journal article
Language:English
Published: 2006