Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders.

Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders.

Spinal muscular atrophy (SMA) is a devastating neuromuscular disease characterised by progressive loss of spinal motor neurons. Mutations in the genes underlying spontaneous bovine and feline models of SMA have recently been described. The clinical and pathological features of these disorders are si...

書誌詳細
主要な著者:	Parkinson, N, Baumer, D, Rose-Morris, A, Talbot, K
フォーマット:	Journal article
言語:	English
出版事項:	2008

類似資料

Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.
著者:: Murray, L, 等
出版事項: (2010)

Spinal muscular atrophies reveal motor neuron vulnerability to defects in ribonucleoprotein handling.
著者:: Anderson, K, 等
出版事項: (2003)

Spinal muscular atrophy.
著者:: Talbot, K, 等
出版事項: (2001)

TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy
著者:: Turner, B, 等
出版事項: (2008)

Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.
著者:: Murray, L, 等
出版事項: (2008)

Chapter 7 Spinal muscular atrophies and hereditary motor neuropathies.
著者:: Talbot, K, 等
出版事項: (2007)

Spinal muscular atrophy: Factors that modulate motor neurone vulnerability
著者:: Wen-Yo Tu, 等
出版事項: (2017-06-01)

TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy
著者:: Ansorge Olaf, 等
出版事項: (2008-10-01)

Review: neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy.
著者:: Murray, L, 等
出版事項: (2010)

Neuronal involvement in muscular atrophy
著者:: Bruno Alejandro Cisterna, 等
出版事項: (2014-12-01)

Inherited Paediatric Motor Neuron Disorders: Beyond Spinal Muscular Atrophy
著者:: Hooi Ling Teoh, 等
出版事項: (2017-01-01)

Chapter 16 Spinal Muscular Atrophy
著者:: Talbot, K, 等
出版事項: (2003)

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.
著者:: Bäumer, D, 等
出版事項: (2009)

Identifying epigenetic regulators of survival motor neuron protein to treat spinal muscular atrophy
著者:: Kordala, A
出版事項: (2022)

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy
著者:: Hor, Jin Hui, 等
出版事項: (2019)

Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.
著者:: Dione T Kobayashi, 等
出版事項: (2011-01-01)

Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients
著者:: Christopher Grunseich, 等
出版事項: (2014-10-01)

Spinal Muscular Atrophy Diagnosed by Newborn Screening
著者:: Matias Lopez-Chacon, 等
出版事項: (2019-12-01)

Spinal muscular atrophy at the crossroads of basic science and therapy
著者:: Sleigh, J, 等
出版事項: (2013)

Spinal muscular atrophy patient iPSC-derived motor neurons have reduced expression of proteins important in neuronal development
著者:: Heidi R Fuller, 等
出版事項: (2016-01-01)

Spinal and bulbar muscular atrophy as a multisystem disease with motor neuron and muscle involvement: literature review and a case report
著者:: E. O. Ivanova, 等
出版事項: (2020-06-01)

Comprehensive In Silico Analysis of Retrotransposon Insertions within the <i>Survival Motor Neuron</i> Genes Involved in Spinal Muscular Atrophy
著者:: Albano Pinto, 等
出版事項: (2022-05-01)

Newborn Screening for Spinal Muscular Atrophy: Variations in Practice and Early Management of Infants with Spinal Muscular Atrophy in the United States
著者:: Craig M. Zaidman, 等
出版事項: (2024-08-01)

Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis
著者:: Andrew P. Tosolini, 等
出版事項: (2017-12-01)

Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy
著者:: Christian M. Simon, 等
出版事項: (2017-12-01)

Spinal Muscular Atrophy
著者:: J Gordon Millichap
出版事項: (1990-02-01)

Spinal muscular atrophy
著者:: D'Amico Adele, 等
出版事項: (2011-11-01)

Spinal muscular atrophy at the crossroads of basic science and therapy.
著者:: Sleigh, J, 等
出版事項: (2013)

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.
著者:: Dirk Bäumer, 等
出版事項: (2009-12-01)

The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy.
著者:: Sleigh, J, 等
出版事項: (2011)

Survival motor neuron protein regulates oxidative stress and inflammatory response in microglia of the spinal cord in spinal muscular atrophy
著者:: Shiori Ando, 等
出版事項: (2020-12-01)

The Alteration of Intrinsic Excitability and Synaptic Transmission in Lumbar Spinal Motor Neurons and Interneurons of Severe Spinal Muscular Atrophy Mice
著者:: Jianli Sun, 等
出版事項: (2019-02-01)

Molecular Analysis of Survival Motor Neuron and Neuronal Apoptosis Inhibitory Protein Genes in Macedonian Spinal Muscular Atrophy Patients
著者:: Kocheva S, 等
出版事項: (2007-01-01)

Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy.
著者:: Andrew J Schwab, 等
出版事項: (2014-01-01)

Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy.
著者:: Sleigh, J, 等
出版事項: (2014)

Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy
著者:: Marina Boido, 等
出版事項: (2018-01-01)

Analysis of the survival of motor neuron (SMN1) gene mutations in Spinal Muscular Atrophy through models
著者:: Owen, N, 等
出版事項: (2002)

Recombinant SMN protein synergizes with spinal muscular atrophy therapy to counteract pathological motor neuron phenotypes
著者:: Liliana Brambilla, 等
出版事項: (2024-12-01)

Improved therapeutic approach for spinal muscular atrophy via ubiquitination‐resistant survival motor neuron variant
著者:: Joonwoo Rhee, 等
出版事項: (2024-08-01)

Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons
著者:: Maria P. Miralles, 等
出版事項: (2022-12-01)