Activation of mitogen activated Protein Kinases (MAPKs) and gene induction upon explantation in articular cartilage from wild type and FGF-2(-/-) mice

Activation of mitogen activated Protein Kinases (MAPKs) and gene induction upon explantation in articular cartilage from wild type and FGF-2(-/-) mice

Manylion Llyfryddiaeth
Prif Awduron:	Chong, K, Didangelos, A, Saklatvala, J, Vincent, T
Fformat:	Journal article
Cyhoeddwyd:	2009

Eitemau Tebyg

Induction of interleukin-1 in articular cartilage by explantation and cutting.
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Articular cartilage injury rapidly activates TAK1 in chondrocytes by inducing its phosphorylation and K63-polyubiquitination
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Detection of Mitogen-activated Protein Kinase (MAPK) Activation upon Exogenous Chemical Application in Arabidopsis Protoplasts
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Sharp injury to articular cartilage activates JNK and NF kappa B and induces expression of inflammatory response genes
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Basic FGF mediates an immediate response of articular cartilage to mechanical injury.
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Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.
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Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage.
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Apolipoprotein A-1 is a novel inducer of aggrecan breakdown in cultured articular cartilage
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Basic fibroblast growth factor (FGF) mediator of the immediate injury response in articular cartilage
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Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link
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BASIC FIBROBLAST GROWTH FACTOR (bFGF) MEDIATES THE IMMEDIATE INJURY RESPONSE IN ARTICULAR CARTILAGE
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The dependence of FGF2 on murine cartilage injury responses
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Analysis of mitogen-activated protein kinase pathways used by interleukin 1 in tissues in vivo: activation of hepatic c-Jun N-terminal kinases 1 and 2, and mitogen-activated protein kinase kinases 4 and 7.
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Analysis of mitogen-activated protein kinase pathways used by interleukin 1 in tissues in vivo: Activation of hepatic c-Jun N-terminal kinases 1 and 2, and mitogen-activated protein kinase kinases 4 and 7
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FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer.
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Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum
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The mitogen-activated protein kinase (MAPK) pathway: role in immune evasion by trypanosomatids
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Role of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation
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Profound translational arrest during cyclical loading of porcine articular cartilage is followed by rebound increased protein synthesis in off loaded explants
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Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells.
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Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38.
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Expanding the Mitogen-Activated Protein Kinase (MAPK) Universe: An Update on MAP4Ks
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Identification, Nomenclature, and Evolutionary Relationships of Mitogen-Activated Protein Kinase (MAPK) Genes in Soybean
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Identification, Nomenclature, and Evolutionary Relationships of Mitogen-Activated Protein Kinase (MAPK) Genes in Soybean
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Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: Its role in tumor progression and apoptosis
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Silica nanoparticles induce endoplasmic reticulum stress response and activate mitogen activated kinase (MAPK) signalling
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p38gamma and p38delta mitogen activated protein kinases (MAPKs), new stars in the MAPK galaxy
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Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway
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Pericellular matrix of articular cartilage. A novel mechanotransduction mechanism in articular chondrocytes?
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Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in Inflammatory Arthritis: A Narrative of the Emergence of MAPK-Activated Protein Kinase Inhibitors (MK2i)
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THE ROLE OF FIBROBLAST GROWTH FACTOR 2 (FGF2) IN THE CELLULAR RESPONSE TO INJURY FOLLOWING MURINE CARTILAGE EXPLANTATION
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Basic fibroblast growth factor: An extracellular mechanotransducer in articular cartilage?
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Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
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The c-jun N-terminal kinase (JNK)-2 controls articular cartilage aggrecan degradation and progression of experimental osteoarthritis
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Cyhoeddwyd: (2014)

Wounding articular cartilage rapidly activates multiple signalling events in chondrocytes involving protein phosphorylation and polyubiquitination
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The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself.
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Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38.
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Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage.
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Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis
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In-silico modelling of the mitogen-activated protein kinase (MAPK) pathway in colorectal cancer: mutations and targeted therapy
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