Getting out of mitosis: Spatial and temporal control of mitotic exit and cytokinesis by PP1 and PP2A
Here, we will review the evidence showing that mitotic exit is initiated by regulated proteolysis and then driven by the PPP family of phosphoserine/threonine phosphatases. Rapid APC/CCDC 20 and ubiquitin-dependent proteolysis of cyclin B and securin initiates sister chromatid separation, the first...
| Huvudupphovsmän: | , , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
Wiley
2019
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