Asymmetric remote C-H functionalization: Use of internal olefins in tandem hydrometallation – isomerization – asymmetric conjugate addition sequences
We describe catalytic asymmetric C–C formation using terminal alkyl-metal nucleophiles generated from internal olefins through a ‘chain-walking’ isomerization mechanism. Hydrometallation of internal olefins with the Schwartz reagent gives the least hindered alkyl-zirconocene after thermal (60°C in T...
| Autores principales: | , , |
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| Formato: | Journal article |
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CSIRO Publishing
2014
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