Defective assembly of class I major histocompatibility complex molecules in an embryonic cell line.

Developmentally regulated expression of the products of the major histocompatibility complex (MHC) is thought to play a key role in maternal tolerance of the fetal allograft. Here we analyze a cell line (EE2H3), derived from early post-implantation-stage mouse embryos, that is defective for MHC clas...

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Bibliographic Details
Main Authors: Bikoff, E, Otten, G, Robertson, E
Format: Journal article
Language:English
Published: 1991