Defective assembly of class I major histocompatibility complex molecules in an embryonic cell line.
Developmentally regulated expression of the products of the major histocompatibility complex (MHC) is thought to play a key role in maternal tolerance of the fetal allograft. Here we analyze a cell line (EE2H3), derived from early post-implantation-stage mouse embryos, that is defective for MHC clas...
Autores principales: | , , |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
1991
|