10-Helical conformations in oxetane beta-amino acid hexamers

The first structural investigations were undertaken on a β-hexapeptide 7 in which the peptide backbone is constrained by cis-substituted oxetane rings. Detailed NMR studies in CDCl3 and C6D6 together with molecular mechanics conformational analysis identify a well-defined left-handed helical structu...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Claridge, T, Goodman, J, Moreno, A, Angus, D, Barker, S, Taillefumier, C, Watterson, M, Fleet, G
Format: Journal article
Sprache:English
Veröffentlicht: 2001