Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

Immature dendritic cells (DCs) sample tissue-specific antigens (TSAs) and process them for "crosspresentation" via major histocompatibility complex (MHC) class I and II molecules. Findings with adoptively transferred T cell receptor (TCR)-transgenic CD8+ T cells in transgenic mice expressi...

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Bibliographic Details
Main Authors: Luckashenak, N, Schroeder, S, Endt, K, Schmidt, D, Mahnke, K, Bachmann, M, Marconi, P, Deeg, C, Brocker, T
Format: Journal article
Language:English
Published: 2008