Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

Immature dendritic cells (DCs) sample tissue-specific antigens (TSAs) and process them for "crosspresentation" via major histocompatibility complex (MHC) class I and II molecules. Findings with adoptively transferred T cell receptor (TCR)-transgenic CD8+ T cells in transgenic mice expressi...

Full description

Bibliographic Details
Main Authors:	Luckashenak, N, Schroeder, S, Endt, K, Schmidt, D, Mahnke, K, Bachmann, M, Marconi, P, Deeg, C, Brocker, T
Format:	Journal article
Language:	English
Published:	2008

Similar Items

CTL priming by CD8(+) and CD8(-) dendritic cells in vivo.
by: Ruedl, C, et al.
Published: (1999)

CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo.
by: Ruedl, C, et al.
Published: (1999)

NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.
by: Hermans, I, et al.
Published: (2003)

Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo.
by: Shakhar, G, et al.
Published: (2005)

Induction of CD4+ T-cell responses by dendritic cells in vivo
by: Suri, R, et al.
Published: (1998)

Harnessing dendritic cells for the induction of transplantation tolerance.
by: Silk, K, et al.
Published: (2009)

Dendritic cells and prospects for transplantation tolerance.
by: Fairchild, P, et al.
Published: (2000)

Visualizing dendritic cell networks in vivo.
by: Lindquist, R, et al.
Published: (2004)

In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen.
by: Drakesmith, H, et al.
Published: (1998)

Harnessing the properties of dendritic cells in the pursuit of immunological tolerance
by: Horton, C, et al.
Published: (2017)

Pharmacological manipulation of dendritic cells in the pursuit of transplantation tolerance.
by: Leishman, A, et al.
Published: (2011)

Immature dendritic cells induce alternative CD4(+) T-cell responses in vivo.
by: Suri, R, et al.
Published: (2001)

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo.
by: Darrasse-Jèze, G, et al.
Published: (2009)

Dissection of T-cell tolerance induction by dendritic cell surface glycoproteins
by: Dustin, M, et al.
Published: (2020)

Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms.
by: Cobbold, S, et al.
Published: (2003)

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo.
by: Tadokoro, C, et al.
Published: (2006)

Cutting Edge: Delay and Reversal of T Cell Tolerance by Intratumoral Injection of Antigen-Loaded Dendritic Cells in an Autochthonous Tumor Model
by: Higham, Eileen M., et al.
Published: (2012)

Antigen-presenting cells. Experimental and clinical studies of dendritic cells.
by: Austyn, J
Published: (2000)

Role of different dendritic cell subsets in vivo
by: Abdul Rashid Mohammad Muzaki
Published: (2015)

Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation.
by: Yates, S, et al.
Published: (2007)

CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens.
by: Salio, M, et al.
Published: (2004)

Antigen presentation by murine dendritic cells is nuclear factor-kappa B dependent both in vitro and in vivo.
by: Yoshimura, S, et al.
Published: (2003)

Improved immune recognition through antigen targeting to the mannose receptor expressed on murine dendritic cells in vivo
by: McKenzie, E, et al.
Published: (2005)

Regulation of antigen-expressing dendritic cells by double negative regulatory T cells.
by: Gao, J, et al.
Published: (2011)

NEW INSIGHTS INTO THE ROLES Of DENDRITIC CELLS IN INTESTINAL IMMUNITY AND TOLERANCE
by: Cerovic, V, et al.
Published: (2009)

New insights into the roles of dendritic cells in intestinal immunity and tolerance.
by: Cerovic, V, et al.
Published: (2009)

Increasing the survival of dendritic cells in vivo does not replace the requirement for CD4+ T cell help during primary CD8+ T cell responses.
by: Matthews, K, et al.
Published: (2007)

Murine cd4+ T cell Responses are inhibited by cytotoxic T cell-mediated killing of dendritic cells and are restored by antigen transfer
by: Ma, Joel Zhi-Iong, et al.
Published: (2013)

Cross presentation of antigen by dendritic cells: mechanisms and implications for immunotherapy.
by: Sachamitr, P, et al.
Published: (2012)

Strategies for antigen choice and priming of dendritic cells influence the polarization and efficacy of antitumor T-cell responses in dendritic cell-based cancer vaccination.
by: Galea-Lauri, J, et al.
Published: (2004)

Immunization with a lentivector that targets tumor antigen expression to dendritic cells induces potent CD8+ and CD4+ T-cell responses.
by: Lopes, L, et al.
Published: (2008)

Antigen-Bearing Dendritic Cells Regulate the Diverse Pattern of Memory CD8 T Cell Development in Different Tissues
by: Shen, Ching-Hung, et al.
Published: (2011)

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141 XCR1 dendritic cells
by: Silk, K, et al.
Published: (2012)

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
by: Silk, K, et al.
Published: (2012)

Dendritic cells in the immune system—history, lineages, tissues, tolerance, and immunity
by: Austyn, J
Published: (2016)

Qa-1(b)-dependent modulation of dendritic cell and NK cell cross-talk in vivo.
by: Colmenero, P, et al.
Published: (2007)

Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: evaluation of dendritic cell-leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination.
by: Galea-Lauri, J, et al.
Published: (2002)

Dendritic cells induce T cell proliferation to synthetic antigens under Ir gene control.
by: Sunshine, G, et al.
Published: (1980)

Peripheral blood dendritic cells express CD52 and are depleted in-vivo by treatment with CAMPATH-1H.
by: Buggins, A, et al.
Published: (2001)

Differential Requirement for CD70 and CD80/CD86 in Dendritic Cellmediated Activation of Tumor Tolerized CD8 T Cells
by: Barnkob, Mike Stein, et al.
Published: (2012)