Structural characterisation of the human alpha-lactalbumin molten globule at high temperature.
Molten globules are partially folded forms of proteins thought to be general intermediates in protein folding. The 15N-1H HSQC NMR spectrum of the human alpha-lactalbumin (alpha-LA) molten globule at pH 2 and 20 degrees C is characterised by broad lines which make direct study by NMR methods difficu...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2003
|