Recombinant human insulin-like growth factor-I abolishes changes in insulin requirements consequent upon growth hormone pulsatility in young adults with type I diabetes mellitus.

To investigate whether recombinant human insulin-like growth factor-I (rhIGF-I) has direct effects on the insulin requirement to maintain euglycemia independent of the growth hormone (GH) level, nine subjects with insulin-dependent diabetes mellitus ([IDDM] seven females; median (range) age, duratio...

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Bibliographic Details
Main Authors: Crowne, E, Samra, J, Cheetham, T, Watts, A, Holly, J, Dunger, D
Format: Journal article
Language:English
Published: 1998