ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.

Patch-clamp recordings and glucagon release measurements were combined to determine the role of plasma membrane ATP-sensitive K+ channels (KATP channels) in the control of glucagon secretion from mouse pancreatic alpha-cells. In wild-type mouse islets, glucose produced a concentration-dependent (hal...

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Bibliographic Details
Main Authors: Gromada, J, Ma, X, Høy, M, Bokvist, K, Salehi, A, Berggren, P, Rorsman, P
Format: Conference item
Published: 2004