Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

The human proteome is a major source of therapeutic targets. Recent genetic association analyses of the plasma proteome enable systematic evaluation of the causal consequences of variation in plasma protein levels. Here we estimated the effects of 1,002 proteins on 225 phenotypes using two-sample Me...

Full description

Bibliographic Details
Main Authors:	Zheng, J, Haberland, V, Baird, D, Walker, V, Haycock, PC, Hurle, MR, Gutteridge, A, Erola, P, Liu, Y, Luo, S, Robinson, J, Richardson, TG, Staley, JR, Elsworth, B, Burgess, S, Sun, BB, Danesh, J, Runz, H, Maranville, JC, Martin, HM, Yarmolinsky, J, Laurin, C, Holmes, MV, Liu, JZ, Estrada, K, Santos, R, McCarthy, L, Waterworth, D, Nelson, MR, Smith, GD, Butterworth, AS, Hemani, G, Scott, RA, Gaunt, TR
Format:	Journal article
Language:	English
Published:	Nature Research 2020

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

Similar Items