Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.

Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.

BACKGROUND and AIMS: Toll-like receptors (TLR) are innate immune receptors involved in recognition of the intestinal microflora; they are expressed by numerous cell types in the intestine, including epithelial cells, myeloid cells, and lymphocytes. Little is known about the relative contributions o...

Полное описание

Библиографические подробности
Главные авторы:	Asquith, M, Boulard, O, Powrie, F, Maloy, K
Формат:	Journal article
Язык:	English
Опубликовано:	2010

Схожие документы

Mouse IBD models reveal distinct pathogenic and protective roles of MyD88 signalling in epithelial cells and leukocytes
по: Asquith, M, и др.
Опубликовано: (2010)

MyD88 signalling from distinct cellular compartments drives intestinal inflammation
по: Asquith, M, и др.
Опубликовано: (2008)

MyD88-dependent pathways in leukocytes affect the retina in diabetes.
по: Jie Tang, и др.
Опубликовано: (2013-01-01)

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.
по: Charles J d'Adhemar, и др.
Опубликовано: (2014-01-01)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
по: Wu Luo, и др.
Опубликовано: (2022-11-01)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
по: Chao Zheng, и др.
Опубликовано: (2020-01-01)

Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure
по: Amber N. Johnson, и др.
Опубликовано: (2023-12-01)

Correction: The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer
Опубликовано: (2014-01-01)

Prognostic significance of MyD88 expression by human epithelial ovarian carcinoma cells
по: Zhu Yi, и др.
Опубликовано: (2012-04-01)

Correction: The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer.
Опубликовано: (2014-01-01)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
по: Junbin Chen, и др.
Опубликовано: (2020-06-01)

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.
по: Timothy Sheahan, и др.
Опубликовано: (2008-12-01)

MyD88 contribution to ocular surface homeostasis.
по: Rose Y Reins, и др.
Опубликовано: (2017-01-01)

MyD 88 Polymorphisms in Children Diagnosed with Sepsis
по: Sinem Sarı Gökay, и др.
Опубликовано: (2016-12-01)

Mechanism of MyD88S mediated signal termination
по: Katarzyna Pustelny, и др.
Опубликовано: (2022-01-01)

MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands.
по: Takeshi Into, и др.
Опубликовано: (2014-01-01)

MyD88 in macrophages protects against colitis via inhibiting the activation of NLRP3 inflammasome in epithelial cells
по: Shi Liu, и др.
Опубликовано: (2023-03-01)

Gut microbiota regulates host melatonin production through epithelial cell MyD88
по: Bingnan Liu, и др.
Опубликовано: (2024-12-01)

Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
по: Kim Ki, и др.
Опубликовано: (2012-09-01)

Blocking MyD88 signaling with MyD88 inhibitor prevents colitis-associated colorectal cancer development by maintaining colonic microbiota homeostasis
по: Bin Xie, и др.
Опубликовано: (2023-12-01)

Pyogenic bacterial infections in humans with MyD88 deficiency.
по: von Bernuth, H, и др.
Опубликовано: (2008)

MyD88 signaling pathways: role in breast cancer
по: Hongmei Zheng, и др.
Опубликовано: (2024-01-01)

MyD88 and Its Inhibitors in Cancer: Prospects and Challenges
по: Jiali Song, и др.
Опубликовано: (2024-05-01)

Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage
по: Iulia Rusu, и др.
Опубликовано: (2022-03-01)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
по: Jiro Sakai, и др.
Опубликовано: (2017-05-01)

Targeting MyD88 Downregulates Inflammatory Mediators and Pathogenic Processes in PBMC From DMARDs-Naïve Rheumatoid Arthritis Patients
по: Sergio Ramirez-Perez, и др.
Опубликовано: (2021-12-01)

Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
по: Takeshi Into, и др.
Опубликовано: (2017-04-01)

T cells in inflammatory bowel disease: protective and pathogenic roles.
по: Powrie, F
Опубликовано: (1995)

MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei.
по: W Joost Wiersinga, и др.
Опубликовано: (2008-01-01)

Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice.
по: Toru Hosoi, и др.
Опубликовано: (2010-01-01)

MyD88-dependent autoimmune disease in Lyn-deficient mice.
по: Silver, K, и др.
Опубликовано: (2007)

MyD88 signalling is critical in the development of pancreatic cancer cachexia
по: Xinxia Zhu, и др.
Опубликовано: (2019-04-01)

Uncoupling between inflammatory and fibrotic responses to silica: evidence from MyD88 knockout mice.
по: Sandra Lo Re, и др.
Опубликовано: (2014-01-01)

Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.
по: George, J, и др.
Опубликовано: (2011)

A Novel Function of TLR2 and MyD88 in the Regulation of Leukocyte Cell Migration Behavior During Wounding in Zebrafish Larvae
по: Wanbin Hu, и др.
Опубликовано: (2021-02-01)

MyD88 Expression by CNS-Resident Cells is Pivotal for Eliciting Protective Immunity in Brain Abscesses
по: Sarita Garg, и др.
Опубликовано: (2009-03-01)

MyD88 is crucial for the development of a protective CNS immune response to <it>Toxoplasma gondii</it> infection
по: Torres Marbel, и др.
Опубликовано: (2013-02-01)

Loss of TLR4 in mouse Müller cells inhibits both MyD88-dependent and -independent signaling.
по: Li Liu, и др.
Опубликовано: (2017-01-01)

Correction: Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice
Опубликовано: (2014-01-01)

IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells
по: Qiong Zhan, и др.
Опубликовано: (2017-03-01)