Exploiting the synergy between carboplatin and ABT-737 in the treatment of ovarian carcinomas
Platinum drug-resistance in ovarian cancers is a major factor contributing to chemotherapeutic resistance of recurrent disease. Members of the Bcl-2 family such as the anti-apoptotic protein Bcl-XL have been shown to play a role in this resistance. Consequently, concurrent inhibition of Bcl-XL in co...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
2012
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