Structural studies on the leukocyte co-stimulatory molecule, B7-1
B7-1 and B7-2 are glycoproteins expressed on antigen presenting cells. The binding of these molecules to the T-cell homodimers, CD28 and CTLA-4, generate 'costimulatory' and inhibitory signals in T cells, respectively. The crystal structure of the extracellular region of B7-1 (sB7-1), solv...
| Egile Nagusiak: | , , , |
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| Formatua: | Conference item |
| Argitaratua: |
2001
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