SPATA2 links CYLD to LUBAC, activates CYLD and controls LUBAC signaling

SPATA2 links CYLD to LUBAC, activates CYLD and controls LUBAC signaling

The Linear UBiquitin chain Assembly Complex (LUBAC) regulates immune signaling and its function is regulated by the deubiquitinases OTULIN and CYLD that associate with the catalytic subunit HOIP. However, the mechanism through which CYLD interacts with HOIP is unclear. We here show that CYLD interac...

書誌詳細
主要な著者:	Elliott, P, Leske, D, Hrdinka, M, Bagola, K, Fiil, B, McLaughlin, S, Wagstaff, J, Volkmar, N, Christianson, J, Kessler, B, Freund, S, Komander, D, Gyrd-Hansen, M
フォーマット:	Journal article
出版事項:	Cell Press 2016

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