Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes.

BACKGROUND: Model organisms have contributed substantially to our understanding of the etiology of human disease as well as having assisted with the development of new treatment modalities. The availability of the human, mouse and, most recently, the rat genome sequences now permit the comprehensiv...

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Bibliographic Details
Main Authors: Huang, H, Winter, E, Wang, H, Weinstock, K, Xing, H, Goodstadt, L, Stenson, P, Cooper, D, Smith, D, Albà, M, Ponting, C, Fechtel, K
Format: Journal article
Language:English
Published: 2004