Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4

CHD4, the core subunit of the Nucleosome Remodelling and Deacetylase (NuRD) complex, is a chromatin remodelling ATPase that, in addition to a helicase domain, harbors tandem plant homeo finger and chromo domains. By using a panel of domain constructs we dissect their roles and demonstrate that DNA b...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Morra, R, Lee, B, Shaw, H, Tuma, R, Mancini, E
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2012