Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.

The speed of virus replication has typically been seen as an advantage for a virus in overcoming the ability of the immune system to control its population growth. Under some circumstances, the converse may also be true: more slowly replicating viruses may evoke weaker cellular immune responses and...

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Bibliographic Details
Main Authors: Bocharov, G, Ludewig, B, Bertoletti, A, Klenerman, P, Junt, T, Krebs, P, Luzyanina, T, Fraser, C, Anderson, R
Format: Journal article
Language:English
Published: 2004