Pillar data‐acquisition strategies for cryo‐electron tomography of beam‐sensitive biological samples
For cryo‐electron tomography (cryo‐ET) of beam‐sensitive biological specimens, a planar sample geometry is typically used. As the sample is tilted, the effective thickness of the sample along the direction of the electron beam increases and the signal‐to‐noise ratio concomitantly decreases, limiting...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
International Union of Crystallography
2024
|