TFH-derived dopamine accelerates productive synapses in germinal centres

Protective high-affinity antibody responses depend on competitive selection of B cells carrying somatically mutated B-cell receptors by follicular helper T (TFH) cells in germinal centres. The rapid T-B-cell interactions that occur during this process are reminiscent of neural synaptic transmission...

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Bibliographic Details
Main Authors: Papa, I, Saliba, D, Ponzoni, M, Bustamante, S, Canete, P, Gonzalez-Figueroa, P, McNamara, H, Valvo, S, Grimbaldeston, M, Sweet, R, Vohra, H, Cockburn, I, Meyer-Hermann, M, Dustin, M, Doglioni, C, Vinuesa, C
Format: Journal article
Language:English
Published: Springer Nature 2017