NRF2 and hypoxia inducible factors: key players in the redox control of systemic iron homeostasis
Significance: Oxygen metabolism and iron homeostasis are closely linked. Iron facilitates the oxygen-carrying capacity of blood, and its deficiency causes anaemia. Conversely, excess free iron is detrimental for stimulating the formation of reactive oxygen species, causing tissue damage. The amount...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Mary Ann Liebert, Inc. Publishers
2020
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