Modulation of osteogenic differentiation in human skeletal cells in Vitro by 5-azacytidine.

Modulation of osteogenic differentiation in human skeletal cells in Vitro by 5-azacytidine.

Cellular differentiation is controlled by a variety of factors including gene methylation, which represses particular genes as cell fate is determined. The incorporation of 5-azacytidine (5azaC) into DNA in vitro prevents methylation and thus can alter cellular differentiation pathways. Human bone m...

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Dettagli Bibliografici
Autori principali:	Locklin, R, Oreffo, R, Triffitt, J
Natura:	Journal article
Lingua:	English
Pubblicazione:	1998

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