A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission

Movement disability in advanced Parkinson's disease (PD) can be treated by high frequency stimulation (HFS) of the subthalamic nucleus (STN) but some patients experience psychiatric side-effects including depression, which is strongly linked to decreases in 5-hydroxytryptamine (5-HT). The curre...

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Bibliographic Details
Main Authors: Tan, S, Hartung, H, Visser-Vandewalle, V, Steinbusch, H, Temel, Y, Sharp, T
Format: Journal article
Language:English
Published: 2012