Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria.

BACKGROUND: Plasmodium falciparum histidine-rich protein PFHRP2 measurement is used widely for diagnosis, and more recently for severity assessment in falciparum malaria. The Pfhrp2 gene is highly polymorphic, with deletion of the entire gene reported in both laboratory and field isolates. These iss...

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Bibliographic Details
Main Authors:	Ramutton, T, Hendriksen, I, Mwanga-Amumpaire, J, Mtove, G, Olaosebikan, R, Tshefu, A, Onyamboko, M, Karema, C, Maitland, K, Gomes, E, Gesase, S, Reyburn, H, Silamut, K, Chotivanich, K, Promnares, K, Fanello, C, von Seidlein, L, Day, N, White, N, Dondorp, A, Imwong, M, Woodrow, C
Format:	Journal article
Language:	English
Published:	BioMed Central 2012

Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria.

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