Structure and substrate specificity of the Pim-1 kinase.

Structure and substrate specificity of the Pim-1 kinase.

अन्य संस्करण दिखाएं (1)

The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3) belonging to the CAMK (calmodulin-dependent protein kinase-related) group. Pim kinases are emerging as important mediators of cytokine signaling pathways in hematopoietic cells, and they contribute...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Bullock, A, Debreczeni, J, Amos, A, Knapp, S, Turk, B
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2005

समान संसाधन

Structure and substrate specificity of the Pim-1 kinase
द्वारा: Bullock, A, और अन्य
प्रकाशित: (2005)

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.
द्वारा: Bullock, A, और अन्य
प्रकाशित: (2005)

Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
द्वारा: Bullock, A, और अन्य
प्रकाशित: (2009)

Ruthenium half-sandwich complexes bound to protein kinase Pim-1
द्वारा: Debreczeni, J, और अन्य
प्रकाशित: (2006)

Ruthenium half-sandwich complexes bound to protein kinase Pim-1.
द्वारा: Debreczeni, J, और अन्य
प्रकाशित: (2006)

Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
द्वारा: Alex N Bullock, और अन्य
प्रकाशित: (2009-10-01)

Electrostatically Enhanced Association of a Pim Kinase Substrate Revealed by Stochastic Detection
द्वारा: Harrington, L, और अन्य
प्रकाशित: (2014)

PIM1 kinase and its diverse substrate in solid tumors
द्वारा: Rituparna Choudhury, और अन्य
प्रकाशित: (2024-11-01)

Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.
द्वारा: Pogacic, V, और अन्य
प्रकाशित: (2007)

Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate.
द्वारा: Harrington, L, और अन्य
प्रकाशित: (2013)

STUDYING THE ROLE OF PIM KINASES IN FLT3-ITD-INDUCED LEUKEMIA REVEALED PIM1 AS REGULATOR OF CXCL12/CXCR4-MEDIATED HOMING AND MIGRATION
द्वारा: Brault, L, और अन्य
प्रकाशित: (2009)

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors.
द्वारा: Akué-Gédu, R, और अन्य
प्रकाशित: (2009)

Crystal structure-guided design of bisubstrate inhibitors and photoluminiscent probes for protein kinases of the PIM family
द्वारा: Nonga, OE, और अन्य
प्रकाशित: (2021)

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
द्वारा: López-Ramos, M, और अन्य
प्रकाशित: (2010)

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
द्वारा: López-Ramos, M, और अन्य
प्रकाशित: (2010)

Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration.
द्वारा: Grundler, R, और अन्य
प्रकाशित: (2009)

Dissecting Proto-Oncogenic PIM Serine/Threonine Kinases in FLT3-ITD-Induced Leukemogenesis: PIM1 Regulates CXCL12/CXCR4-Mediated Homing and Migration
द्वारा: Gasser, C, और अन्य
प्रकाशित: (2008)

Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure
द्वारा: Lori, C, और अन्य
प्रकाशित: (2013)

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
द्वारा: Bullock, A, और अन्य
प्रकाशित: (2009)

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation
द्वारा: Bullock, A, और अन्य
प्रकाशित: (2009)

Selective bisubstrate inhibitors with sub-nanomolar affinity for protein kinase Pim-1.
द्वारा: Ekambaram, R, और अन्य
प्रकाशित: (2013)

Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family
द्वारा: Olivier E. Nonga, और अन्य
प्रकाशित: (2021-07-01)

Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure.
द्वारा: Clorinda Lori, और अन्य
प्रकाशित: (2013-01-01)

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights (September, pg 3175, 2010)
द्वारा: Lopez-Ramos, M, और अन्य
प्रकाशित: (2011)

Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture.
द्वारा: Eswaran, J, और अन्य
प्रकाशित: (2008)

Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
द्वारा: Bataille, C, और अन्य
प्रकाशित: (2017)

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers.
द्वारा: Brault, L, और अन्य
प्रकाशित: (2010)

Targeting PIM Kinases to Improve the Efficacy of Immunotherapy
द्वारा: Amber N. Clements, और अन्य
प्रकाशित: (2022-11-01)

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.
द्वारा: Brault, L, और अन्य
प्रकाशित: (2012)

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma
द्वारा: Brault, L, और अन्य
प्रकाशित: (2012)

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
द्वारा: Laurent Brault, और अन्य
प्रकाशित: (2010-06-01)

PIM kinases mediate resistance to cisplatin chemotherapy in hepatoblastoma
द्वारा: Raoud Marayati, और अन्य
प्रकाशित: (2021-03-01)

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA.
द्वारा: Fang Cheng, और अन्य
प्रकाशित: (2009-03-01)

PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1
द्वारा: Kwan Long Mung, और अन्य
प्रकाशित: (2021-06-01)

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion
द्वारा: Prudhomme Michelle, और अन्य
प्रकाशित: (2010-10-01)

Expression and ERG regulation of PIM kinases in prostate cancer
द्वारा: Sini K. Eerola, और अन्य
प्रकाशित: (2021-05-01)

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma
द्वारा: Ulrike Weirauch, और अन्य
प्रकाशित: (2013-07-01)

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma
द्वारा: Ulrike Weirauch, और अन्य
प्रकाशित: (2013-07-01)

Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity
द्वारा: Peltola Katriina J, और अन्य
प्रकाशित: (2006-05-01)

Synthesis of Fused Quinoline Derivatives With Antiproliferative Activities and Tyrosine Kinases, Pim-1 Kinase Inhibitions
द्वारा: Rafat Milad Mohareb, और अन्य
प्रकाशित: (2022-03-01)